| Rubric Capital Management LP |
DELAWARE |
8000000 |
8000000 |
8000000 |
0 |
8000000 |
8.06 % |
15/05/2026 |
| BlackRock, Inc. |
DELAWARE |
0 |
0 |
0 |
0 |
4946412 |
4.98 % |
27/04/2026 |
| Integrated Core Strategies (US) LLC |
DELAWARE |
5194497 |
5194497 |
5194497 |
0 |
5194497 |
5.2 % |
31/03/2026 |
| Millennium Management LLC |
DELAWARE |
5391440 |
5391440 |
5391440 |
0 |
5391440 |
5.4 % |
24/03/2026 |
| Rubric Capital Management LP |
DELAWARE |
6200000 |
6200000 |
6200000 |
0 |
6200000 |
6.27 % |
13/02/2026 |
| BlackRock, Inc. |
DELAWARE |
0 |
0 |
0 |
0 |
5013000 |
5.1 % |
21/01/2026 |
| RA Capital Healthcare Fund, L.P. |
DE |
0 |
9958073 |
0 |
9958073 |
9958073 |
10.1 % |
01/10/2025 |
| RA Capital Management, L.P. |
DE |
0 |
10940977 |
0 |
10940977 |
10940977 |
11.1 % |
01/10/2025 |
| Peter Kolchinsky |
UNITED STATES |
0 |
10940977 |
0 |
10940977 |
10940977 |
11.1 % |
01/10/2025 |
| Rajeev Shah |
UNITED STATES |
0 |
10940977 |
0 |
10940977 |
10940977 |
11.1 % |
01/10/2025 |
| Deerfield Mgmt III, L.P. |
DE |
0 |
3805108 |
0 |
3805108 |
3805108 |
3.87 % |
01/08/2025 |
| Deerfield Private Design Fund III, L.P. |
DE |
0 |
3805108 |
0 |
3805108 |
3805108 |
3.87 % |
01/08/2025 |
| Deerfield Mgmt IV, L.P. |
DE |
0 |
3805109 |
0 |
3805109 |
3805109 |
3.87 % |
01/08/2025 |
| Deerfield Private Design Fund IV, L.P. |
DE |
0 |
3805109 |
0 |
3805109 |
3805109 |
3.87 % |
01/08/2025 |
| Deerfield Management Company, L.P. |
DE |
0 |
7610217 |
0 |
7610217 |
7610217 |
7.75 % |
01/08/2025 |
| James E. Flynn |
UNITED STATES |
0 |
7610217 |
0 |
7610217 |
7610217 |
7.75 % |
01/08/2025 |
| James E. Flynn |
UNITED STATES |
0 |
8633537 |
0 |
8633537 |
8633537 |
8.79 % |
22/07/2025 |
| Deerfield Private Design Fund III, L.P. |
DE |
0 |
4316768 |
0 |
4316768 |
4316768 |
4.4 % |
22/07/2025 |
| Deerfield Mgmt IV, L.P. |
DE |
0 |
4316769 |
0 |
4316769 |
4316769 |
4.4 % |
22/07/2025 |
| Deerfield Mgmt III, L.P. |
DE |
0 |
4316768 |
0 |
4316768 |
4316768 |
4.4 % |
22/07/2025 |
| Deerfield Private Design Fund IV, L.P. |
DE |
0 |
4316769 |
0 |
4316769 |
4316769 |
4.4 % |
22/07/2025 |
| Deerfield Management Company, L.P. |
DE |
0 |
8633537 |
0 |
8633537 |
8633537 |
8.79 % |
22/07/2025 |
| Deerfield Mgmt III, L.P. |
DE |
0 |
4862254 |
0 |
4862254 |
4862254 |
4.95 % |
02/07/2025 |
| Deerfield Private Design Fund III, L.P. |
DE |
0 |
4862254 |
0 |
4862254 |
4862254 |
4.95 % |
02/07/2025 |
| Deerfield Mgmt IV, L.P. |
DE |
0 |
4862254 |
0 |
4862254 |
4862254 |
4.95 % |
02/07/2025 |
| Deerfield Private Design Fund IV, L.P. |
DE |
0 |
4862254 |
0 |
4862254 |
4862254 |
4.95 % |
02/07/2025 |
| Deerfield Management Company, L.P. |
DE |
0 |
9724508 |
0 |
9724508 |
9724508 |
9.9 % |
02/07/2025 |
| James E. Flynn |
UNITED STATES |
0 |
9724508 |
0 |
9724508 |
9724508 |
9.9 % |
02/07/2025 |
| Deerfield Mgmt IV, L.P. |
DE |
0 |
5257328 |
0 |
5257328 |
5257328 |
5.36 % |
24/03/2025 |
| Deerfield Mgmt III, L.P. |
DE |
0 |
5257329 |
0 |
5257329 |
5257329 |
5.36 % |
24/03/2025 |
| Deerfield Private Design Fund III, L.P. |
DE |
0 |
5257329 |
0 |
5257329 |
5257329 |
5.36 % |
24/03/2025 |
| Deerfield Private Design Fund IV, L.P. |
DE |
0 |
5257328 |
0 |
5257328 |
5257328 |
5.36 % |
24/03/2025 |
| Deerfield Management Company, L.P. |
DE |
0 |
10514657 |
0 |
10514657 |
10514657 |
10.72 % |
24/03/2025 |
| James E. Flynn |
UNITED STATES |
0 |
10514657 |
0 |
10514657 |
10514657 |
10.72 % |
24/03/2025 |
| RA Capital Management, L.P. |
Delaware |
0 |
6759678 |
0 |
10 |
6759678 |
7.07 % |
31/08/2023 |
| RA Capital Healthcare Fund, L.P. |
States |
0 |
5856774 |
0 |
10 |
5856774 |
6.13 % |
31/08/2023 |
| Rajeev Shah |
States |
0 |
6759678 |
0 |
10 |
6759678 |
7.07 % |
31/08/2023 |
| Peter Kolchinsky |
or Place of Organization. United States |
0 |
6759678 |
0 |
10 |
6759678 |
7.07 % |
31/08/2023 |
